病變二尖瓣的水利特性研究.doc
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病變二尖瓣的水利特性研究,1.48萬字自己原創(chuàng)的畢業(yè)論文，僅在本站獨(dú)家出售，重復(fù)率低，推薦下載使用摘要 二尖瓣是人體心臟的重要瓣膜組織，二尖瓣脫垂是指二尖瓣葉（前葉、后葉或兩葉）在心室收縮期脫入左心房（向左房側(cè)膨出），伴或不伴有二尖瓣關(guān)閉不全二尖瓣反流，會(huì)造成左心室擴(kuò)張以及左心室功能障礙，一般而言約有10-20%的人有這...
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此文檔由會(huì)員 淘寶大夢(mèng) 發(fā)布
病變二尖瓣的水利特性研究
1.48萬字
自己原創(chuàng)的畢業(yè)論文，僅在本站獨(dú)家出售，重復(fù)率低，推薦下載使用
摘要 二尖瓣是人體心臟的重要瓣膜組織，二尖瓣脫垂是指二尖瓣葉（前葉、后葉或兩葉）在心室收縮期脫入左心房（向左房側(cè)膨出），伴或不伴有二尖瓣關(guān)閉不全二尖瓣反流，會(huì)造成左心室擴(kuò)張以及左心室功能障礙，一般而言約有10-20%的人有這種現(xiàn)象，但是絕大部分的人都無癥狀，本身并無太大的的研究意義與必要,而二尖瓣腱索斷裂幾乎總是導(dǎo)致急性、常常是嚴(yán)重的二尖瓣返流,或使慢性二尖瓣返流急性惡化.所以研究二尖瓣腱索斷裂的特性對(duì)于病態(tài)二尖瓣病因的檢測(cè)以及臨床修復(fù)手術(shù)具有十分重要的指導(dǎo)意義.而由于生理系統(tǒng)本身的復(fù)雜機(jī)制以及生物體檢測(cè)的困難我們不得不利用電路模擬仿真進(jìn)行量化分析[1]。而傳統(tǒng)的電路模擬系統(tǒng)一般是用一個(gè)二極管串接一個(gè)線性或者非線性電阻這樣的簡(jiǎn)單模型來模擬。這種方法主要是模擬血液的單向流動(dòng)特性。但是卻忽略了諸如血液回流.瓣膜物理特征等重要特性。本文則采用的是實(shí)驗(yàn)臺(tái)控制水壓模擬瓣膜兩端壓力變化進(jìn)行水利實(shí)驗(yàn),從而得到相對(duì)準(zhǔn)確的二尖瓣特性曲線。
本文首先介紹了實(shí)驗(yàn)的一些背景資料如當(dāng)前的研究成果以及對(duì)本次實(shí)驗(yàn)的指導(dǎo)意義。而后對(duì)整個(gè)實(shí)驗(yàn)的過程以及整個(gè)實(shí)驗(yàn)裝置的調(diào)整進(jìn)行了闡述和分析，對(duì)實(shí)驗(yàn)結(jié)果也進(jìn)行了初步的處理,隨后還將根據(jù)流體特性對(duì)結(jié)果進(jìn)一步處理以得到更為準(zhǔn)確的二尖瓣特性曲線。
本次實(shí)驗(yàn)的主要工作意義在于利用水流模擬血液流動(dòng),并且利用真實(shí)豬心二尖瓣進(jìn)行實(shí)驗(yàn),回避了電路模型對(duì)于瓣膜生物特性的仿真不完全,能夠更準(zhǔn)確的測(cè)量出液體通過腱索斷裂二尖瓣時(shí)壓力流量的變化,對(duì)于二尖瓣乃至整個(gè)左心血液循環(huán)系統(tǒng)的仿真建模有著重要指導(dǎo)作用。
關(guān)鍵詞：病變二尖瓣 腱索斷裂 房室壓差 血液流量方向 二尖瓣的特性曲線
Study on Hydraulic characteristics of The Diseased Mitral
Abstract Mitral valve tissue is an important part of human heart , mitral valve prolapse is the mitral valve (anterior , posterior lobe or both lobes ) in ventricular systole off into the left atrium ( left atrial side bulging ) , with or without mitral regurgitation mitral regurgitation can cause left ventricular dilatation and left ventricular dysfunction , in general , about 10-20 % of people have this phenomenon, but most people are asymptomatic itself is not much research significance and necessary, and mitral valve chordae rupture almost always lead to acute , often severe mitral regurgitation , or to acute exacerbation of chronic mitral regurgitation , so research two mitral valve chordae rupture properties for the detection of pathological etiology and clinical mitral valve repair surgery has a very important significance . rather difficult due to the complex biological mechanisms and physiological detection system itself we had to use circuit simulation quantitative analysis . The traditional circuit simulation system is generally a diode in series with a linear or non-linear resistance of such a simple model to simulate . This method is to simulate the characteristics of one-way flow of blood . But it ignores the important features such as the backflow of blood . Valvular physical characteristics.
This paper adopts the bench hydraulic control valve simulation experiment ends of Water Conservancy pressure changes , resulting in relatively accurate mitral valve characteristic curve.This paper describes the experimental paper first introduces some background information such as the current research and guidance for this experiment . Then for several changes throughout the experiment and the adjustment of the entire experimental setup are described and analyzed , the experimental results have also been preliminary processing , fluid properties will then be further processed in accordance with the results to obtain more accurate mitral characteristic curve.
The main significance of this experiment is to use hydraulic simulation of blood flow , and use real pig heart mitral experiment avoided the circuit model for the biological characteristics of the valve ignored , can more accurately measure the liquid through the mitral chordae rupture changes in pressure and flow valve , the mitral valve for simulation modeling and the whole left heart circulatory system plays an important role in guiding .
Key words： Mitral valve disease Chordal rupture Atrioventricular pressure Blood flow direction Mitral valve characteristic curve
目 錄
第一章 緒論 1
1.1 二尖瓣腱索斷裂的研究歷史及發(fā)展現(xiàn)狀 1
1.1.1 二尖瓣腱索斷裂研究的發(fā)展?fàn)顩r 1
1.1.2 心血管建模仿真技術(shù)的現(xiàn)況 1
1.2 課題研究的背景、主要內(nèi)容及意義 2
1.2.1 課題研究的背景 2
1.2.2 課題的主要研究?jī)?nèi)容及意義 4
1.3 小結(jié) 4
第二章 經(jīng)由二尖瓣的血液循環(huán)原理結(jié)構(gòu) 5
2.1左心血液循環(huán)過程 5
2.2 二尖瓣的模型 6
2.3 模擬左心環(huán)境的實(shí)驗(yàn)裝置整體設(shè)計(jì) 6
2.4 小結(jié) 7
第三章 實(shí)驗(yàn)裝置設(shè)計(jì)及實(shí)驗(yàn)流程 8
3.1 實(shí)驗(yàn)總體設(shè)計(jì) 8
3.2靜態(tài)實(shí)驗(yàn)裝置搭建 8
3.3動(dòng)態(tài)實(shí)驗(yàn)裝置搭建 12
第四章 實(shí)驗(yàn)步驟 16
4.1實(shí)驗(yàn)準(zhǔn)備及注意事項(xiàng) 16
4.1.1二尖瓣數(shù)據(jù)記錄 16
4.1.2二尖瓣解剖流程 16
4.1.3 二尖瓣安裝步驟 17
4.2 靜態(tài)實(shí)驗(yàn) 18
4.2.1 靜態(tài)正向?qū)嶒?yàn)過程 18
4.2.2 靜態(tài)返流實(shí)驗(yàn)過程 19
4.3動(dòng)態(tài)實(shí)驗(yàn) 20
4.4 小結(jié)和實(shí)驗(yàn)結(jié)果預(yù)測(cè) 21
第五章 實(shí)驗(yàn)結(jié)果及分析 22
5.1 實(shí)驗(yàn)設(shè)計(jì) 22
5.2 系統(tǒng)測(cè)試調(diào)試 22-..
1.48萬字
自己原創(chuàng)的畢業(yè)論文，僅在本站獨(dú)家出售，重復(fù)率低，推薦下載使用
摘要 二尖瓣是人體心臟的重要瓣膜組織，二尖瓣脫垂是指二尖瓣葉（前葉、后葉或兩葉）在心室收縮期脫入左心房（向左房側(cè)膨出），伴或不伴有二尖瓣關(guān)閉不全二尖瓣反流，會(huì)造成左心室擴(kuò)張以及左心室功能障礙，一般而言約有10-20%的人有這種現(xiàn)象，但是絕大部分的人都無癥狀，本身并無太大的的研究意義與必要,而二尖瓣腱索斷裂幾乎總是導(dǎo)致急性、常常是嚴(yán)重的二尖瓣返流,或使慢性二尖瓣返流急性惡化.所以研究二尖瓣腱索斷裂的特性對(duì)于病態(tài)二尖瓣病因的檢測(cè)以及臨床修復(fù)手術(shù)具有十分重要的指導(dǎo)意義.而由于生理系統(tǒng)本身的復(fù)雜機(jī)制以及生物體檢測(cè)的困難我們不得不利用電路模擬仿真進(jìn)行量化分析[1]。而傳統(tǒng)的電路模擬系統(tǒng)一般是用一個(gè)二極管串接一個(gè)線性或者非線性電阻這樣的簡(jiǎn)單模型來模擬。這種方法主要是模擬血液的單向流動(dòng)特性。但是卻忽略了諸如血液回流.瓣膜物理特征等重要特性。本文則采用的是實(shí)驗(yàn)臺(tái)控制水壓模擬瓣膜兩端壓力變化進(jìn)行水利實(shí)驗(yàn),從而得到相對(duì)準(zhǔn)確的二尖瓣特性曲線。
本文首先介紹了實(shí)驗(yàn)的一些背景資料如當(dāng)前的研究成果以及對(duì)本次實(shí)驗(yàn)的指導(dǎo)意義。而后對(duì)整個(gè)實(shí)驗(yàn)的過程以及整個(gè)實(shí)驗(yàn)裝置的調(diào)整進(jìn)行了闡述和分析，對(duì)實(shí)驗(yàn)結(jié)果也進(jìn)行了初步的處理,隨后還將根據(jù)流體特性對(duì)結(jié)果進(jìn)一步處理以得到更為準(zhǔn)確的二尖瓣特性曲線。
本次實(shí)驗(yàn)的主要工作意義在于利用水流模擬血液流動(dòng),并且利用真實(shí)豬心二尖瓣進(jìn)行實(shí)驗(yàn),回避了電路模型對(duì)于瓣膜生物特性的仿真不完全,能夠更準(zhǔn)確的測(cè)量出液體通過腱索斷裂二尖瓣時(shí)壓力流量的變化,對(duì)于二尖瓣乃至整個(gè)左心血液循環(huán)系統(tǒng)的仿真建模有著重要指導(dǎo)作用。
關(guān)鍵詞：病變二尖瓣 腱索斷裂 房室壓差 血液流量方向 二尖瓣的特性曲線
Study on Hydraulic characteristics of The Diseased Mitral
Abstract Mitral valve tissue is an important part of human heart , mitral valve prolapse is the mitral valve (anterior , posterior lobe or both lobes ) in ventricular systole off into the left atrium ( left atrial side bulging ) , with or without mitral regurgitation mitral regurgitation can cause left ventricular dilatation and left ventricular dysfunction , in general , about 10-20 % of people have this phenomenon, but most people are asymptomatic itself is not much research significance and necessary, and mitral valve chordae rupture almost always lead to acute , often severe mitral regurgitation , or to acute exacerbation of chronic mitral regurgitation , so research two mitral valve chordae rupture properties for the detection of pathological etiology and clinical mitral valve repair surgery has a very important significance . rather difficult due to the complex biological mechanisms and physiological detection system itself we had to use circuit simulation quantitative analysis . The traditional circuit simulation system is generally a diode in series with a linear or non-linear resistance of such a simple model to simulate . This method is to simulate the characteristics of one-way flow of blood . But it ignores the important features such as the backflow of blood . Valvular physical characteristics.
This paper adopts the bench hydraulic control valve simulation experiment ends of Water Conservancy pressure changes , resulting in relatively accurate mitral valve characteristic curve.This paper describes the experimental paper first introduces some background information such as the current research and guidance for this experiment . Then for several changes throughout the experiment and the adjustment of the entire experimental setup are described and analyzed , the experimental results have also been preliminary processing , fluid properties will then be further processed in accordance with the results to obtain more accurate mitral characteristic curve.
The main significance of this experiment is to use hydraulic simulation of blood flow , and use real pig heart mitral experiment avoided the circuit model for the biological characteristics of the valve ignored , can more accurately measure the liquid through the mitral chordae rupture changes in pressure and flow valve , the mitral valve for simulation modeling and the whole left heart circulatory system plays an important role in guiding .
Key words： Mitral valve disease Chordal rupture Atrioventricular pressure Blood flow direction Mitral valve characteristic curve
目 錄
第一章 緒論 1
1.1 二尖瓣腱索斷裂的研究歷史及發(fā)展現(xiàn)狀 1
1.1.1 二尖瓣腱索斷裂研究的發(fā)展?fàn)顩r 1
1.1.2 心血管建模仿真技術(shù)的現(xiàn)況 1
1.2 課題研究的背景、主要內(nèi)容及意義 2
1.2.1 課題研究的背景 2
1.2.2 課題的主要研究?jī)?nèi)容及意義 4
1.3 小結(jié) 4
第二章 經(jīng)由二尖瓣的血液循環(huán)原理結(jié)構(gòu) 5
2.1左心血液循環(huán)過程 5
2.2 二尖瓣的模型 6
2.3 模擬左心環(huán)境的實(shí)驗(yàn)裝置整體設(shè)計(jì) 6
2.4 小結(jié) 7
第三章 實(shí)驗(yàn)裝置設(shè)計(jì)及實(shí)驗(yàn)流程 8
3.1 實(shí)驗(yàn)總體設(shè)計(jì) 8
3.2靜態(tài)實(shí)驗(yàn)裝置搭建 8
3.3動(dòng)態(tài)實(shí)驗(yàn)裝置搭建 12
第四章 實(shí)驗(yàn)步驟 16
4.1實(shí)驗(yàn)準(zhǔn)備及注意事項(xiàng) 16
4.1.1二尖瓣數(shù)據(jù)記錄 16
4.1.2二尖瓣解剖流程 16
4.1.3 二尖瓣安裝步驟 17
4.2 靜態(tài)實(shí)驗(yàn) 18
4.2.1 靜態(tài)正向?qū)嶒?yàn)過程 18
4.2.2 靜態(tài)返流實(shí)驗(yàn)過程 19
4.3動(dòng)態(tài)實(shí)驗(yàn) 20
4.4 小結(jié)和實(shí)驗(yàn)結(jié)果預(yù)測(cè) 21
第五章 實(shí)驗(yàn)結(jié)果及分析 22
5.1 實(shí)驗(yàn)設(shè)計(jì) 22
5.2 系統(tǒng)測(cè)試調(diào)試 22-..
